Profhilo has the highest concentration of hyaluronic acid on the market and delivers a prolonged efficacy without the addition of cross-linking chemical agents.

Profhilo is Quality and safety by design.

ULTRAPURE hyaluronic acid in compliance with European and FDA standards.

Profhilo is Biocomptible.

It integrates into the tissue to restore hyaluronic acid levels naturally found in the skin.

Profhilo is Effective. 

Clinical data confirm improvements in skin texture, elasticty and hydration with immediate tightening effect.

Profhilo is Non-Invasive.

A specially developed injection technique reduces pain, downtime and the number of treatment sessions, making it the perfect lunch-time procedure.

Client comments:

“Reduced the number of Treatment sessions”

“Reduced number of injecton sites, therefore reduced discomfort per session”

“Reduced or eliminated downtime”

“Optimal results visible after only 2 treatments”

More facts about Profhilo....
Profhilo has the Highest concentration of HA in the market…

Profhilo contains 32mg of low molecular weight
HA (80-100Kda) and 32 mg of high molecular
weight HA (1100-1400Kda). This gives one of
the highest concentrations of HA on the market
totalling 64 mg of HA in a 2ml prefilled syringe.
Remarkably this can still be extruded using a
29g needle.

Profhilo is stabilised by…

Profhilo is developed by using a patented
technology resulting in hybrid cooperative
complexes between high molecular weight
HA and low molecular HA without the use of
any chemical cross-linking compounds. These
complexes increase the stability of HA to
enzymatic and mechanical degradation.

Profhilo’s Nahyco technology…

Thermal cross-linking changes the character and behavior of the HA resulting in the formation of co-operative hybrid complexes which modulate the tissues. This is also the explanation for the different biological behaviour with respect to H-HA and L-HA alone.

One of the main advantages is longevity. Hybrid cooperative complexes have proven to be very stable with natural hyaluronidase (BTH) digestion when compared to H-HA, widely used in biorevitalisation products, or L-HA alone
resulting in the long-lasting release and the
dual action of the two HA components. This
dual action is ideal for remodelling skin laxity.

Profhilo’s advantages…

In Profhilo, L-HA is released slowly from the
HA hybrid complexes and therefore does
not trigger the first inflammatory cytokines,
making it very biocompatible. It also
increases patient comfort during and after
treatment and provides hydration to the skin
– the Hydro effect.

H-HA in Profhilo provides a stable HA
architecture in the dermis. This gives a
volumetric effect – the Lift effect.

Another advantage of the stable co-operative
hybrid complex when compared to H-HA and
L-HA is the increase in the expression levels
of type I and type III collagen in fibroblast and
type IV and VII collagen in keratinocytes.
This results in improved skin quality and skin
hydration both in the dermis and epidermis.
There is also increased production of
endogenous HA and elastin giving the skin a
more youthful look.

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